So-called silent diseases, such as Inborn Errors of Immunity (IEI), represent a double challenge: not only due to their biological complexity, but also because their symptoms often go unnoticed—even when they cause a profound impact on the lives of patients and families.

Beyond Symptoms: The Social and Emotional Impact

Many patients go through a cycle of medical appointments, inconclusive tests, and late diagnoses, which creates frustration and emotional strain. The invisibility of the disease—both in society and sometimes within the healthcare system itself—increases the risk of social isolation and chronic anxiety.

How Medicine Is Evolving in Response to Silent Diseases

Recent advances in genetics and immunology have made it possible to identify specific mutations that cause IEI. Genetic testing and immunophenotyping panels now help predict complications before they become severe. This knowledge enables earlier, more personalized, and more effective interventions.

The Need for Multidisciplinary Support

Dealing with silent diseases requires more than just a diagnosis. Comprehensive care includes:

• Clinical and immunological care: ongoing evaluation of immune markers and infection prevention

• Psychological support: helping patients cope with anxiety, fear of complications, and the impact on family life

• Physical therapy and functional care: strategies to maintain quality of life, strength, and mobility

• Legal and social support: ensuring access to specialized medications, therapies, and patients’ rights

Why Talk About Silent Diseases?

Awareness of these conditions allows for early detection, fewer complications, and a transformed patient journey. At the same time, educating society builds empathy and strengthens support networks—reminding us that health is not only the absence of visible symptoms, but overall well-being.

Pró-Raros: Support That Transforms the Journey

Facing a silent disease can feel lonely and overwhelming, but no one has to go through it alone. At Pró-Raros, we connect patients and families with a qualified network of professionals who provide clinical, emotional, physical, and legal support—ensuring personalized, comprehensive care.

More than information, we offer guidance, compassion, and practical solutions that improve quality of life, transforming the impact of illness into a safer and more hopeful journey.

If you are a patient or family member seeking support, or simply want to learn more about how we can help, get in touch with our team.